Autophagy in tumour suppression and promotion
نویسندگان
چکیده
منابع مشابه
Autophagy in tumour suppression and promotion.
Autophagy, a well-described cellular mechanism for lysosomal degradation of cytoplasmic content, has emerged as a tumour suppression pathway. Recent evidence indicates that the tumour suppressor function of autophagy is mediated by scavenging of damaged oxidative organelles, thereby preventing accumulation of toxic oxygen radicals that would cause genome instability. Paradoxically, however, in ...
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ژورنال
عنوان ژورنال: Molecular Oncology
سال: 2009
ISSN: 1574-7891
DOI: 10.1016/j.molonc.2009.05.007